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Discuss and critically analyse how newly born neurons contribute to adult brain function in humans and why their continuous renewa
INTRODUCTION (~300 words)
• Adult neurogenesis: definition, historical approaches
• Introduction of the hippocampus
• Hippocampal neurogenesis as present focus of the essay
• Brief introduction to Spalding et al study as starting point (Spalding et al., 2013)
BODY (~1000 words)
• Brief discussion and analysis of Spalding study
o Methodology (nuclear bomb)
o Key findings
• The functions of adult hippocampal neurogenesis
• Discuss some environmental factors that can influence adult hippocampal neurogenesis
• Other advances that has been used to investigate neurogenesis among adult humans [, zebrafish, rodents] since 2013
o in relation to neurodegenerative and neurocognitive disorders (i.e. epilepsy (Danzer, 2019)
o in area of deferring aging (memory loss, decline in cognitive functions etc)
o in relation to depression and addictions
CONCLUSION (~200 words)
• Advances in the neuroscience successfully challenge he past conclusions that brain cells, including neurons, develop mainly during childhood
• Hippocampal neurogenesis provides a good base for further understanding, investigating, diagnosing, and treating various neurological conditions/disorders/diseases affecting humankind
• Future is in further research and empirical studies to better understand the nature of neurogenesis and to expand its potential
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